COVID-19: comments on official social network of the Ministry of Health about action Brazil Count on Me.

OBJECTIVE: To unveil the content of comments in official posts calling from the Ministry of Helth, calling for health professionals to confront COVID-19. METHOD: Qualitative study, carried out with 2823 comments, obtained from the virtual access to the Ministry of Health's social networks on Facebook, Instagram and Twitter. For textual corpus processing, used or software Interface R analyzes Multidimensional Texts and Questionnaires and performs a multivariate analysis by Descending Hierarchical Classification. RESULTS: Five categories were included: "difficulties in the training stages", "aspects involved in the summons", "working conditions without facing the pandemic", "mandatory capacity x possible summons", "visibility and valorization of dentistry in combating the pandemic" COVID-19". CONCLUSION: Comments contemplated professionals or access to training, remuneration and working conditions, mandatory training, possibility of calling for action on the front line without fighting COVID-19 and claiming greater appreciation of dentistry.

Estudos experimentais sobre COVID-19: panorama da produção científica mundial

Resumo Objetivo Descrever o panorama mundial da produção de estudos experimentais relacionados à COVID-19. Métodos Estudo descritivo, realizado em abril de 2020, a partir de busca pelos registros de ensaios clínicos, nos portais Clinical Trials e Registros Brasileiros de Ensaios Clínicos. A análise estatística foi descritiva. Resultados Dos 645 ensaios clínicos da amostra, houve predominância de 199 (30,9%) oriundos da Europa, 213 (33%) realizados por instituições hospitalares, 482 (74,7%) com objetivo direcionado ao tratamento. Quanto às intervenções pesquisadas, 394 (61,1%) foram sobre medicamentos;70 (10,8%) investigaram intervenções biológicas;45 (7,0%), intervenções com sangue e derivados;40 (6,2%), intervenções comportamentais;38 (5,9%), intervenções com equipamentos;31(4,8%), intervenções assistenciais/procedimentais;18 (2,8%), intervenções para diagnóstico e nove (1,4%), intervenções de suplementação dietética. Observou-se que, em 515 (79,8%) a população estudada foi composta por adultos e idosos, 635 (98,4%) investigaram ambos os sexos, o delineamento de 480 (74,4%) incluiu randomização, de 482 (74,7%) alocação paralela dos participantes e 373 (57,8%) não possuíu o cegamento. Conclusão Os estudos experimentais sobre a COVID-19 foram oriundos da Europa, realizados por hospitais, sobre o tratamento em adultos e idosos, com randomização, mas sem cegamento. Os achados podem direcionar a realização de estudos, para contemplarem as lacunas identificadas. Resumen Objetivo Describir el panorama mundial de la producción de estudios experimentales relacionados con la COVID-19. Métodos Estudio descriptivo, realizado en abril de 2020, a partir de la búsqueda de registros de ensayos clínicos en los portales Clinical Trials y Registros Brasileiros de Ensaios Clínicos. El análisis estadístico fue descriptivo. Resultados De los 645 ensayos clínicos de la muestra, hubo predominancia de 199 (30,9 %) oriundos de Europa, 213 (33 %) realizados por instituciones hospitalarias, 482 (74,7 %) con objetivo orientado al tratamiento. Respecto a las intervenciones investigadas, 394 (61,1 %) fueron sobre medicamentos;70 (10,8 %) investigaron intervenciones biológicas;45 (7,0 %), intervenciones con sangre y derivados;40 (6,2 %), intervenciones de comportamiento;38 (5,9 %), intervenciones con equipos;31 (4,8 %), intervenciones asistenciales/procedimentales;18 (2,8 %), intervenciones para diagnóstico, y 9 (1,4 %), intervenciones de suplementos dietéticos. Se observó que en 515 ensayos (79,8 %) la población estudiada fue compuesta por adultos y ancianos, en 635 (98,4 %) se investigaron ambos sexos, el diseño de 480 (74,4 %) incluyó aleatorización, de 482 (74,7 %) asignación paralela de los participantes y 373 (57,8 %) no poseían cegamiento. Conclusión Los estudios experimentales sobre la COVID-19 fueron oriundos de Europa, realizados por hospitales, sobre el tratamiento en adultos y ancianos, con aleatorización, pero sin cegamiento. Los resultados pueden orientar la realización de estudios que contemplen los vacíos identificados. Objective To describe the world panorama of the production of experimental studies on COVID-19. Methods Descriptive study conducted in April 2020, based on a search for clinical trial records on the Clinical Trials and Brazilian Clinical Trials Records portals. The statistical analysis was descriptive. Results Of the 645 clinical trials in the sample, there was a predominance of 199 (30.9%) from Europe, 213 (33%) performed by hospital institutions, 482 (74.7%) with the objective aimed at the treatment. As for interventions surveyed, 394 (61.1%) were on drugs;70 (10.8%) investigated biological interventions;45 (7.0%) interventions with blood and blood products;40 (6.2%), behavioral interventions;38 (5.9%), interventions with equipment;31 (4.8%), care/procedural interventions;18 (2.8%), diagnostic interventions and nine (1.4%) dietary supplementation interventions. The studied population was composed of adult and elderly subjects in 515 (79.8%) studies, 635 (98.4%) investigated both sexes, the design of 480 (74.4%) included randomization, of 482 (74.7%) parallel allocation of participants and 373 (57.8%) did not have blinding. Conclusion The experimental studies on COVID-19 originated from Europe, were conducted by hospitals, on treatment in adult and elderly subjects, with randomization but without blinding. The findings may direct the performance of studies addressing the identified gaps.

Experimental studies on COVID-19: overview of the world scientific production

Resumo Objetivo Descrever o panorama mundial da produção de estudos experimentais relacionados à COVID-19. Métodos Estudo descritivo, realizado em abril de 2020, a partir de busca pelos registros de ensaios clínicos, nos portais Clinical Trials e Registros Brasileiros de Ensaios Clínicos. A análise estatística foi descritiva. Resultados Dos 645 ensaios clínicos da amostra, houve predominância de 199 (30,9%) oriundos da Europa, 213 (33%) realizados por instituições hospitalares, 482 (74,7%) com objetivo direcionado ao tratamento. Quanto às intervenções pesquisadas, 394 (61,1%) foram sobre medicamentos;70 (10,8%) investigaram intervenções biológicas;45 (7,0%), intervenções com sangue e derivados;40 (6,2%), intervenções comportamentais;38 (5,9%), intervenções com equipamentos;31(4,8%), intervenções assistenciais/procedimentais;18 (2,8%), intervenções para diagnóstico e nove (1,4%), intervenções de suplementação dietética. Observou-se que, em 515 (79,8%) a população estudada foi composta por adultos e idosos, 635 (98,4%) investigaram ambos os sexos, o delineamento de 480 (74,4%) incluiu randomização, de 482 (74,7%) alocação paralela dos participantes e 373 (57,8%) não possuíu o cegamento. Conclusão Os estudos experimentais sobre a COVID-19 foram oriundos da Europa, realizados por hospitais, sobre o tratamento em adultos e idosos, com randomização, mas sem cegamento. Os achados podem direcionar a realização de estudos, para contemplarem as lacunas identificadas. Resumen Objetivo Describir el panorama mundial de la producción de estudios experimentales relacionados con la COVID-19. Métodos Estudio descriptivo, realizado en abril de 2020, a partir de la búsqueda de registros de ensayos clínicos en los portales Clinical Trials y Registros Brasileiros de Ensaios Clínicos. El análisis estadístico fue descriptivo. Resultados De los 645 ensayos clínicos de la muestra, hubo predominancia de 199 (30,9 %) oriundos de Europa, 213 (33 %) realizados por instituciones hospitalarias, 482 (74,7 %) con objetivo orientado al tratamiento. Respecto a las intervenciones investigadas, 394 (61,1 %) fueron sobre medicamentos;70 (10,8 %) investigaron intervenciones biológicas;45 (7,0 %), intervenciones con sangre y derivados;40 (6,2 %), intervenciones de comportamiento;38 (5,9 %), intervenciones con equipos;31 (4,8 %), intervenciones asistenciales/procedimentales;18 (2,8 %), intervenciones para diagnóstico, y 9 (1,4 %), intervenciones de suplementos dietéticos. Se observó que en 515 ensayos (79,8 %) la población estudiada fue compuesta por adultos y ancianos, en 635 (98,4 %) se investigaron ambos sexos, el diseño de 480 (74,4 %) incluyó aleatorización, de 482 (74,7 %) asignación paralela de los participantes y 373 (57,8 %) no poseían cegamiento. Conclusión Los estudios experimentales sobre la COVID-19 fueron oriundos de Europa, realizados por hospitales, sobre el tratamiento en adultos y ancianos, con aleatorización, pero sin cegamiento. Los resultados pueden orientar la realización de estudios que contemplen los vacíos identificados. Objective To describe the world panorama of the production of experimental studies on COVID-19. Methods Descriptive study conducted in April 2020, based on a search for clinical trial records on the Clinical Trials and Brazilian Clinical Trials Records portals. The statistical analysis was descriptive. Results Of the 645 clinical trials in the sample, there was a predominance of 199 (30.9%) from Europe, 213 (33%) performed by hospital institutions, 482 (74.7%) with the objective aimed at the treatment. As for interventions surveyed, 394 (61.1%) were on drugs;70 (10.8%) investigated biological interventions;45 (7.0%) interventions with blood and blood products;40 (6.2%), behavioral interventions;38 (5.9%), interventions with equipment;31 (4.8%), care/procedural interventions;18 (2.8%), diagnostic interventions and nine (1.4%) dietary supplementation interventions. The studied population was composed of adult and elderly subjects in 515 (79.8%) studies, 635 (98.4%) investigated both sexes, the design of 480 (74.4%) included randomization, of 482 (74.7%) parallel allocation of participants and 373 (57.8%) did not have blinding. Conclusion The experimental studies on COVID-19 originated from Europe, were conducted by hospitals, on treatment in adult and elderly subjects, with randomization but without blinding. The findings may direct the performance of studies addressing the identified gaps.

Experimental studies on COVID-19: overview of the world scientific production Estudios experimentales sobre COVID-19: panorama de la producción científica mundial

Abstract Objective To describe the world panorama of the production of experimental studies on COVID-19. Methods Descriptive study conducted in April 2020, based on a search for clinical trial records on the Clinical Trials and Brazilian Clinical Trials Records portals. The statistical analysis was descriptive. Results Of the 645 clinical trials in the sample, there was a predominance of 199 (30.9%) from Europe, 213 (33%) performed by hospital institutions, 482 (74.7%) with the objective aimed at the treatment. As for interventions surveyed, 394 (61.1%) were on drugs;70 (10.8%) investigated biological interventions;45 (7.0%) interventions with blood and blood products;40 (6.2%), behavioral interventions;38 (5.9%), interventions with equipment;31 (4.8%), care/procedural interventions;18 (2.8%), diagnostic interventions and nine (1.4%) dietary supplementation interventions. The studied population was composed of adult and elderly subjects in 515 (79.8%) studies, 635 (98.4%) investigated both sexes, the design of 480 (74.4%) included randomization, of 482 (74.7%) parallel allocation of participants and 373 (57.8%) did not have blinding. Conclusion The experimental studies on COVID-19 originated from Europe, were conducted by hospitals, on treatment in adult and elderly subjects, with randomization but without blinding. The findings may direct the performance of studies addressing the identified gaps.